Review: low-dose thiazides are the most effective first-line drugs for hypertension

Thiazides first-line treatment for hypertension.

879 D la Chronique numéro 47, nous avons étudié les données scientifiques tirées de tous les essais contrôlés randomisés sur l’hypertension comparant les thiazidiqu de première intention avec les inhibiteurs de l’enzyme de conversion de l’angiotensine (IECA) et les inhibiteurs calciques (IC). Nous avons mis l’accent sur l’étude ALLHAT (traitement antihypertenseur et hypolipidémiant pour préveni...

Review: Low-dose diuretics are the best first-line antihypertensive therapy.

Are beta-blockers efficacious as first-line therapy for hypertension in the elderly? A systematic review.

OBJECTIVE To assess antihypertensive efficacy of beta-blockers and their effects on cardiovascular morbidity and mortality and all-cause morbidity compared with diuretics in elderly patients with hypertension. DATA SOURCE A MEDLINE search of English-language articles published between January 1966 and January 1998 using the terms hypertension (drug therapy) and elderly or aged or geriatric, a...

Are thiazides effective on hypertensive vertigo? A preliminary study.

OBJECTIVES In this study, we aimed to investigate whether the symptoms of vertigo related to hypertension resulted from endolymphatic hydrops and the efficacy of the thiazides in the treatment. PATIENTS AND METHODS A total of 24 vertigo patients without peripheric or central vestibular pathologies or hyperlipidemia were included. The study group comprised 15 patients with hypertension, includ...

What alternatives to first-line therapy for depression are effective?

Depression is often a chronic illness that requires a methodical, long-term approach to manage it optimally. A single antidepressant trial is often insufficient for patients to achieve remission. Remission rates for selective serotonin reuptake inhibitors are about 30% to 35%. Using successive treatment steps with optimal medication dosing and making measurement-based treatment decisions can he...